Nellie Saluda McKenzie Sanders was a pioneering African American nurse and public health advocate in Charlotte, North Carolina. Born on November 19, 1894, in Greensboro, she was the daughter of Professor Rufus McKenzie and Lucy Ann Edwell McKenzie. She graduated from the Lincoln Hospital School of Nursing in 1909 and passed the state nursing boards in 1925 . In 1918, Sanders served as a public health nurse employed by the Home Service Section and the Negro Chamber of Commerce in Charlotte, focusing on general nursing care for the African American community . She was actively involved in professional nursing organizations, attending the organizational meeting of the North Carolina Association of Colored Graduate Nurses (NCACGN) in 1923 and participating in various conventions and discussions throughout the 1920s and 1930s. While specific records of her role as the first nursing supervisor at Good Samaritan Hospital in Charlotte are not readily available, her extensive involvement in public health nursing and leadership within the African American nursing community suggest she held significant positions in healthcare institutions serving Charlotte’s Black population during the early to mid-20th century.